1- 4 The incidence of development of fulminant colitis has been reported to be as high as three percent, with toxic megacolon being a common clinical manifestation of systemic disease.
C diff colonoscopy findings full#
1, 2 In the past decade, it has become one of the major causes of nosocomial diarrhea and displays a full spectrum of symptoms ranging from asymptomatic to fulminant colitis with systemic toxicity and death. difficile), is a gram-positive, anaerobic, spore-forming bacterium identified as the cause of antibiotic associated diarrhea and pseudomembranous colitis in the late 1970s. Key WordsĬlostridium difficile, complicated Clostridium difficile, diverting loop ileostomy, colonic lavage Abbreviationsįecal microbiota transplantation (FMT) Case DescriptionĬlostridium difficile (C. difficile colitis increases and strains evolve, providing combination treatment modalities to combat hypervirulence may be considered to preserve the colon in select patients. In this case, a diverting loop ileostomy with colonic lavage was complimented with postoperative fecal transplantation via the diverting loop ileostomy. difficile infection requiring emergent surgical intervention. difficile colitis and progression to a fulminant C. This is a single case of sigmoid diverticulitis with superimposed development of C. The patient was treated with a combination of a diverting loop ileostomy with intraoperative colonic lavage of high-volume polyethylene glycol followed by postoperative antegrade instillation of vancomycin flushes via the ileostomy, in addition to postoperative fecal microbiota transplantation. The patient continued to decline clinically despite aggressive medical therapy, leading to failure of nonoperative treatment. Clinical deterioration prompted further workup revealing superimposed C. SummaryĪ 52-year-old female was admitted for sigmoid diverticulitis and initially responded well to parenteral broad-spectrum antibiotics and bowel rest. difficile colitis requiring emergent surgical intervention. difficile) infectious colitis, and she progressed to fulminant C. A 52-year-old female with sigmoid diverticulitis developed superimposed Clostridium difficile (C.
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